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Updated: Apr 4, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
M-mode apical systolic excursion: A new and simple method to evaluate global left ventricular longitudinal strain
José Amado1, Fabián Islas1, Islas Leopoldo Pérez de Isla2
1Cardiology Department, Hospital Clínico San Carlos, Madrid, Spain.
M-mode measurements like mitral annular plane systolic excursion (MAPSE) and apical systolic excursion (MMASE) correlate with left ventricular longitudinal strain (LVLS). These simpler echocardiographic methods can help predict subclinical left ventricular systolic dysfunction.
Area of Science:
- Cardiology
- Echocardiography
- Cardiac Mechanics
Background:
- M-mode echocardiography offers regional left ventricular deformation assessment.
- Hypothesized correlation between M-mode parameters (MMASE, MAPSE) and LVLS.
Purpose of the Study:
- To investigate the correlation between MMASE, MAPSE, and LVLS.
- To evaluate simpler echocardiographic methods for predicting subclinical left ventricular systolic dysfunction.
Main Methods:
- Echocardiographic evaluation including MMASE and MAPSE measurements.
- Three-dimensional wall motion tracking (3D-WMT) for LVLS assessment.
Main Results:
- Significant correlations found between MAPSE and LVLS (r=-0.372, p=0.04).
- Significant correlations found between MMASE and LVLS (r=-0.398, p=0.027).
- Linear relationships established: ST = -10.6 - 0.4*MAPSE (r²=0.14) and ST = -13.1 - 0.5*MMASE (r²=0.16).
Conclusions:
- Simpler M-mode measurements (MAPSE, MMASE) correlate with LVLS.
- These methods may predict subclinical left ventricular systolic dysfunction.
- Potential alternative to complex strain analysis for early detection of cardiac dysfunction.
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