Related Experiment Video
Updated: Apr 4, 2026

A Technical Guide for Performing Spectroscopic Measurements on Metal-Organic Frameworks
Published on: April 28, 2023
A novel type of matrix for surface-assisted laser desorption-ionization mass spectrometric detection of biomolecules
Chien-Ping Fu1, Stephen Lirio1, Wan-Ling Liu1
1Department of Chemistry, Chung Yuan Christian University, Chung Li District, Taoyuan City, 320, Taiwan.
Abstract:
A 3D metal-organic framework (MOF) nanomaterial as matrix for surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) and tandem mass spectrometry (MS/MS) was developed for the analysis of complex biomolecules. Unlike other nanoparticle matrices, this MOF nanomaterial does not need chemical modification prior to use. An exceptional signal reproducibility as well as very low background interferences in analyzing mono-/di-saccharides, peptides and complex starch digests demonstrate its high potential for biomolecule assays, especially for small molecules.
More Related Videos
06:45Author Spotlight: Characterizing Porous Materials for Aiding the Development of Robust Metal-Organic Frameworks with Adsorption Behavior
Published on: March 8, 2024
09:38Dithranol as a Matrix for Matrix Assisted Laser Desorption/Ionization Imaging on a Fourier Transform Ion Cyclotron Resonance Mass Spectrometer
Published on: November 26, 2013
Related Concept Videos
MALDI-TOF Mass Spectrometry
Matrix-Assisted Laser Desorption Ionization (MALDI)