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Updated: Aug 14, 2026

An In Vitro Organ Culture Model of the Murine Intervertebral Disc
Published on: April 11, 2017
[Biomechanical relation of the intervertebral disk, intervertebral foramen and vertebral canal: an experimental study
Abstract:
For the purpose of observing the biomechanical relationship among intervertebral disk (D), intervertebral foramen (F) and vertebral canal (C), 11 sets of functional unit of lumbar spine from fresh cadavers were used as specimens in this experiment. The data showed that the DFC were closely related in dimensional changes with different loadings, a phenomenon we call it DFC variation reaction. It was shown that the loading axes in the disk and in the inter-articular joints worked together biomechanically as an isosceles triangle to accommodate the stresses applied. The mechanism of the relapsed symptoms of protruded intervertebral disk after diskectomy, and of that of spinal canal stenosis was discussed. A reasonable operation for treatment of these maladies has been suggested.
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