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Related Concept Videos

Role of Skin in Vitamin D Synthesis01:23

Role of Skin in Vitamin D Synthesis

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
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Mutations01:35

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Mutations are changes in the sequence of DNA. These changes can occur spontaneously or they can be induced by exposure to environmental factors. Mutations can be characterized in a number of different ways: whether and how they alter the amino acid sequence of the protein, whether they occur over a small or large area of DNA, and whether they occur in somatic cells or germline cells.
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Vitamins01:30

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Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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Energy Transfer in Chemical Reactions01:16

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Chemical reactions require sufficient energy to cause the matter to collide with enough precision and force that old chemical bonds can be broken and new ones formed. In general, kinetic energy is the form of energy powering any type of matter in motion. Imagine a person building a brick wall. The energy it takes to lift and place one brick on top of another is the kinetic energy—the energy matter possesses because of its motion. Once the wall is in place, it stores potential energy.
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Studying Chronic Exposure of Mice to Ultraviolet B Radiation
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Sunshine and vitamin D.

Vrinda Saraff1, Nick Shaw1

  • 1Department of Endocrinology and Diabetes, Birmingham Children's Hospital, Birmingham, UK.

Archives of Disease in Childhood
|September 2, 2015
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Summary
This summary is machine-generated.

Vitamin D deficiency is a growing health concern impacting bone health. This review covers factors affecting skin vitamin D production and recommendations for safe sun exposure and supplementation.

Keywords:
Bone DiseaseDermatologyEndocrinology

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Area of Science:

  • Endocrinology
  • Dermatology
  • Public Health

Background:

  • Vitamin D is crucial for bone health.
  • Vitamin D deficiency, once thought eradicated, is now a significant public health issue.
  • The primary source of vitamin D is skin exposure to solar ultraviolet B (UVB) radiation, with limited contribution from diet.

Purpose of the Study:

  • To review factors influencing vitamin D synthesis in the skin.
  • To outline recommendations for safe sun exposure to optimize vitamin D levels.
  • To discuss dietary supplementation strategies for achieving adequate vitamin D for bone health.

Main Methods:

  • Literature review of factors affecting cutaneous vitamin D synthesis.
  • Analysis of current recommendations for sun exposure and vitamin D supplementation.
  • Synthesis of evidence regarding optimal vitamin D levels for bone health.

Main Results:

  • Multiple factors influence the efficiency of vitamin D production in the skin.
  • Current guidelines emphasize balancing sun exposure risks with vitamin D benefits.
  • Dietary intake and supplementation are important adjuncts to sun exposure.

Conclusions:

  • Addressing vitamin D deficiency requires a multifaceted approach.
  • Personalized recommendations for sun exposure and supplementation are key for maintaining bone health.
  • Public health strategies should focus on education regarding vitamin D sources and risks.