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Updated: Apr 4, 2026

MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
Published on: October 7, 2025
[Novel micro RNA-based therapies for the treatment of neuroblastoma]
Ariadna Boloix1, Laia París-Coderch1, Aroa Soriano1
1Grupo de Investigación Traslacional en el Cáncer de la infancia y adolescencia, Institut de Recerca, Vall d'Hebron, Barcelona, España.
Abstract:
Neuroblastoma (NB) is the most common solid tumour in children and adolescents, and accounts for up to 15% of all cancer deaths in this group. It originates in the sympathetic nervous system, and its behaviour can be very aggressive and become resistant to current treatments. A review is presented, summarising the new alternative therapies based on epigenetics, i.e., modulators of gene expression, such as microRNAs and their potential application in the clinical practice of NB treatment.
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