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Oral polyp as the presenting feature of Beckwith-Wiedemann syndrome in a child

Omar Kujan1, Syed Ahmed Raheel2, David King3

  • 1Department of Oral and Maxillofacial Sciences, Al-Farabi Colleges, Riyadh, Saudi Arabia.

BMJ Case Reports
|September 2, 2015
PubMed

Insights

Beckwith-Wiedemann syndrome (BWS), a congenital overgrowth disorder, can manifest with rare oral polyps. This case highlights the importance of considering BWS in children with oral polyps and other characteristic features.

Area of Science:

  • Pediatric Endocrinology
  • Genetics
  • Developmental Biology

Background:

  • Beckwith-Wiedemann syndrome (BWS) is a rare congenital overgrowth disorder.
  • Key features include abdominal wall defects, macroglossia, and somatic gigantism.
  • Gastrointestinal and urinary tract polyps are recognized, but oral manifestations are undocumented.

Observation:

  • This report details the first documented case of an oral polyp in a patient with Beckwith-Wiedemann syndrome.
  • The patient presented with an oral polyp alongside other potential BWS indicators.

Findings:

  • The occurrence of an oral polyp is a novel finding in the spectrum of Beckwith-Wiedemann syndrome.
  • This expands the known clinical manifestations associated with BWS.

Implications:

  • Pediatricians and clinicians should consider BWS in the differential diagnosis of children presenting with oral polyps.
  • Early recognition of BWS is crucial for timely management and monitoring of associated health risks.

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