Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

2.4K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.4K
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

1.6K
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.6K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.7K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.7K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

1.0K
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
1.0K
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

182
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
182

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anaphylaxis Clinical Care Pathway: Incorporating Intranasal Epinephrine (Adrenaline).

The journal of allergy and clinical immunology. In practice·2026
Same author

IgE-Mediated Legume Allergy in Children: Insights from a Single-Center Experience in Italy.

Nutrients·2026
Same author

Pragmatic Strategies for Reducing Variability and Risk in Food Oral Immunotherapy.

Clinical reviews in allergy & immunology·2026
Same author

Current postpartum management of hypertension: A survey of obstetricians, general practitioners, and midwives in the UK.

Pregnancy hypertension·2026
Same author

Age-Appropriate Low Dosing for Food Protein-Induced Enterocolitis Syndrome Oral Food Challenges: Proposing a Standardized Approach.

The journal of allergy and clinical immunology. In practice·2026
Same author

World Allergy Organization survey on the diagnosis and management trends of perioperative anaphylaxis.

The World Allergy Organization journal·2026

Related Experiment Video

Updated: Apr 4, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K

Current controversies and challenges in allergic rhinitis management.

David Price1, Pete Smith2, Peter Hellings3

  • 1a 1 Research in Real Life, Singapore, Singapore.

Expert Review of Clinical Immunology
|September 2, 2015
PubMed
Summary

Effective allergic rhinitis (AR) management faces challenges including inadequate symptom relief and over-reliance on clinical trials. This review addresses these issues, proposing solutions for better AR control.

Keywords:
allergic rhinitisclinical relevancecontrolguidelinesrandomized controlled trialsreal life

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K
Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.9K

Related Experiment Videos

Last Updated: Apr 4, 2026

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.2K
Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.9K

Area of Science:

  • Allergy and immunology
  • Clinical research methodology

Background:

  • Current allergic rhinitis (AR) treatments offer insufficient symptom relief for some patients in real-world settings.
  • Existing AR management guidelines heavily depend on randomized controlled trials (RCTs), potentially overlooking real-life effectiveness.

Purpose of the Study:

  • To review the obstacles in effective allergic rhinitis control.
  • To challenge current practices and propose solutions for improved AR management.

Main Methods:

  • Comprehensive review of existing literature, including RCTs and real-life studies.
  • Critical analysis of study designs, interpretation, and guideline development in AR management.

Main Results:

  • Identified key challenges: insufficient symptom relief, over-reliance on RCTs, need for broader evidence interpretation, study design flaws, and lack of a unified control concept.
  • Highlighted controversies surrounding AR management strategies.

Conclusions:

  • Effective AR control requires a broader interpretation of evidence beyond RCTs.
  • Development of a common language and concept for AR control is essential for improved patient outcomes.