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Computer-based HIV adherence promotion interventions: a systematic review: Translation Behavioral Medicine
Kasey R Claborn1, Anne Fernandez2, Tyler Wray2
1Center for Alcohol and Addiction Studies and the Alcohol Research Center on HIV, Brown University, Providence, RI 02912 USA ; 121 South Main Street, Providence, RI 02903 USA.
Translational Behavioral Medicine
|September 2, 2015
Summary
Computer-based interventions show promise for improving HIV adherence. While feasible and acceptable, more rigorous research is needed to confirm their clinical effectiveness in people with HIV.
Area of Science:
- Public Health
- Health Informatics
- Behavioral Science
Background:
- Access to HIV adherence interventions is crucial for managing the condition.
- Computer-based delivery offers a scalable approach to disseminate these interventions.
Purpose of the Study:
- To systematically review studies on computer-delivered interventions for HIV adherence.
- To assess the feasibility, acceptability, and efficacy of these interventions.
Main Methods:
- Systematic review of five databases for studies published through January 2014.
- Inclusion criteria focused on computer-based delivery of HIV adherence interventions.
- Analysis of ten identified studies including RCTs, pilot, and feasibility studies.
Main Results:
- Interventions varied significantly in structure, theory, and content.
- Six studies reported medication adherence outcomes; four showed significant improvement.
- Computer-delivered interventions were found to be feasible and acceptable for adults and adolescents with HIV.
Conclusions:
- Computer-delivered HIV adherence interventions appear feasible and acceptable.
- Current evidence is limited by the small number of adequately powered randomized trials.
- Further randomized controlled research is necessary to establish definitive clinical impact and efficacy.

