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Feedback Inhibition00:46

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Biochemical reactions are occurring constantly in cells, converting starting substances to different products, usually with the help of enzymes that speed the reactions. Without enzymes, it would take far too long for most reactions to occur to be useful to the cell!
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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Scanning Skeletal Remains for Bone Mineral Density in Forensic Contexts
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Authors' reply

Rachel Upthegrove1, Ian Jones1, Nick Craddock1

  • 1Rachel Upthegrove, Department of Psychiatry, School of Clinical & Experimental Medicine, University of Birmingham, Birmingham, Bipolar Disorder Research Network and Early Intervention Service, Birmingham and Solihull Mental Health Foundation Trust, Birmingham, UK. Email: R.Upthegrove@bham.ac.uk; Ian Jones, Nick Craddock, National Centre for Mental Health, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff and Bipolar Disorder Research Network, UK.

The British Journal of Psychiatry : the Journal of Mental Science
|September 3, 2015
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No abstract available in PubMed .

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