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Induction and Clinical Scoring of Chronic-Relapsing Experimental Autoimmune Encephalomyelitis

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Published on: July 4, 2007

Bickerstaff's Brainstem Encephalitis - A Case Report.

G K Kundu¹, M M Rahman, B K Paul

¹Dr Gopen Kumar Kundu, Assistant Professor, Paediatric Neurology Unit, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh.

Mymensingh Medical Journal : MMJ

|September 3, 2015

Summary

This summary is machine-generated.

Bickerstaff

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Area of Science:

Neurology
Pediatrics
Infectious Diseases

Background:

Bickerstaff's brainstem encephalitis (BBE) is a rare autoimmune neurological disorder.
It is characterized by a triad of symptoms: ophthalmoplegia, ataxia, and altered consciousness.
Early diagnosis and treatment are crucial for favorable outcomes.

Observation:

An 11-year-old male presented with fever, headache, vertigo, and seizures.
Clinical examination revealed drowsiness, somnolence, ophthalmoplegia, exaggerated reflexes, and ataxia.
Cerebrospinal fluid (CSF) showed mild pleocytosis; brain MRI indicated left midbrain hyperintensity.

Findings:

The clinical presentation, CSF findings, and MRI results strongly suggested Bickerstaff's brainstem encephalitis.
The patient exhibited a rare neurological condition with overlapping symptoms of encephalitis and Guillain-Barré syndrome.
Routine investigations were normal, highlighting the importance of specific neurological assessments.

Implications:

This case underscores the importance of recognizing rare neurological disorders like BBE in pediatric patients.
Prompt diagnosis through a combination of clinical, biochemical, and radiological findings is essential.
Highlighting rare diseases aids clinicians in differential diagnosis and timely management.