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Published on: April 5, 2018
[A clinical case of pulmonary thromboembolism in a patient at risk treated with rt-pA]
Abstract:
After a brief mention of new advances in the pathophysiology of fibrinolysis, the authors outline the pharmacological properties of the new thrombolytic agent rt-pA versus classic thrombolytic agent urokinase and streptokinase. Thereafter they report a case of acute pulmonary embolism with severe hypoxemia in a patient with a history of recent traumatic cerebral bleeding. Thrombolytic treatment with rt-pA (100 mg/2 h) resulted in a satisfactory clinical outcome without appreciable worsening of intracranial injury.
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