[Ocular changes in children with acute lymphoblastic leukemia].

Area of Science:

• Ophthalmology
• Pediatric Hematology
• Oncology

Context:

• Acute lymphoblastic leukemia (ALL) is a common childhood cancer.
• Ocular complications can arise during various stages of ALL.
• Understanding these changes is crucial for comprehensive patient care.

Purpose:

• To investigate the occurrence and nature of eye changes in children with acute lymphoblastic leukemia.
• To assess the impact of disease recurrence on ocular microcirculation.
• To evaluate the therapeutic effect of specific treatments on these eye changes.

Summary:

• Children diagnosed with acute lymphoblastic leukemia (ALL) exhibit ocular alterations throughout the disease's progression.
• Biomicroscopy revealed impaired blood flow within conjunctival vessels, more pronounced in patients experiencing ALL relapses.
• Administration of antiaggregants, angioprotectors, and general therapy positively modulated the microcirculation in ocular vessels.

Impact:

• Early detection of specific eye changes in ALL patients can enhance overall diagnosis.
• Targeted ocular assessments may lead to improved diagnostic accuracy and additional therapeutic strategies.
• Monitoring ocular microcirculation provides insights into disease status and treatment efficacy in pediatric ALL.