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Thalidomide in angiodysplasia-related bleeding

J P Boey1, U Hahn2, S Sagheer3

  • 1Department of Haematology, Flinders Medical Centre, Adelaide, South Australia, Australia.

Internal Medicine Journal
|September 3, 2015
PubMed

Gastrointestinal haemorrhage from angiodysplastic lesions is not only difficult to identify, but often refractory to endoscopic intervention. Patients often require substantial transfusion support. Thalidomide has emerged as a promising medical strategy in angiodysplasia-related bleeding. We present our experience and report the findings from a review of the literature. Despite its side-effect profile, thalidomide remains the therapeutic modality with the best evidence in this difficult clinical scenario.

Keywords:
Von Willebrand diseaseangiodysplasiagastrointestinal haemorrhagethalidomide

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