Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Vascular Spasm01:16

Vascular Spasm

4.8K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
4.8K
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

532
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
532

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of Chronic Subdural Hematoma With Adjunctive Embolization of Middle Meningeal Artery: The EMMA-Can Randomized Clinical Trial.

JAMA·2026
Same author

A randomized trial comparing endovascular and surgical management of ruptured intracranial aneurysms excluded from previous trials.

Journal of neurosurgery·2025
Same author

Conservative management of brain arteriovenous malformations: results of the prospective observation registry of a pragmatic trial.

Journal of neurosurgery·2024
Same author

Pragmatic trials can address diagnostic controversies: recent lessons from gestational diabetes.

Trials·2022
Same author

The Utility of Superselective Rotational Angiography for Frameless Stereotactic Navigation During Craniotomy for Micro-Arteriovenous Malformation.

World neurosurgery: X·2022
Same author

Middle Cerebral Artery Aneurysm Trial (MCAAT): A Randomized Care Trial Comparing Surgical and Endovascular Management of MCA Aneurysm Patients.

World neurosurgery·2021
Same journal

A Neuronal Perspective.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Diagnostic efficacy, costs, and safety of portable ultra-low field MRI in brain imaging: a systematic review.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Chronology of Non-Motor Symptoms in 100 Patients with Advanced PD of 10 Years' Duration: Pre- versus Post-Motor Period.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Chorea-Acanthocytosis: From Motor to Behavioral and Olfactory Profiles.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Outcomes of Acute Ischemic Stroke in Patients with Hematological Malignancies.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
Same journal

Facial Neuropathy in Patients with Recurrent Painful Ophthalmoplegic Neuropathy.

The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques·2026
See all related articles

Related Experiment Video

Updated: Apr 4, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
08:12

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

8.5K

Cerebral Vasospasm: A Review.

J Max Findlay1, Joshua Nisar1, Tim Darsaut1

  • 1University of Alberta Hospital - Medicine,Edmonton,Alberta,Canada.

The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques
|September 3, 2015
PubMed
Summary
This summary is machine-generated.

Cerebral vasospasm after subarachnoid hemorrhage can cause ischemia, but current treatments like nimodipine and angioplasty offer management. Despite research, new drugs have not improved patient outcomes.

Keywords:
cerebral ischemiacerebral vasospasmintracranial aneurysmsubarachnoid hemorrhage

More Related Videos

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

4.3K
A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage
07:03

A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage

Published on: January 17, 2013

14.9K

Related Experiment Videos

Last Updated: Apr 4, 2026

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage
08:12

A Volumetric Method for Quantification of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage

Published on: July 28, 2018

8.5K
Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound
10:41

Analysis of Cerebral Vasospasm in a Murine Model of Subarachnoid Hemorrhage with High Frequency Transcranial Duplex Ultrasound

Published on: June 3, 2021

4.3K
A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage
07:03

A Low Mortality Rat Model to Assess Delayed Cerebral Vasospasm After Experimental Subarachnoid Hemorrhage

Published on: January 17, 2013

14.9K

Area of Science:

  • Neurology
  • Neurosurgery
  • Vascular Medicine

Background:

  • Cerebral vasospasm, a delayed narrowing of cerebral arteries post-subarachnoid hemorrhage, is a major cause of ischemic stroke.
  • Pathogenesis involves hematoma encasement of arteries, with complex interactions not fully understood.
  • Delayed onset offers a window for prevention strategies.

Purpose of the Study:

  • To review current understanding and management of cerebral vasospasm following subarachnoid hemorrhage.
  • To evaluate the efficacy of recent therapeutic interventions.

Main Methods:

  • Review of current literature and clinical trial data on cerebral vasospasm management.
  • Analysis of outcomes associated with pharmacological and interventional treatments.

Main Results:

  • Recent trials of clazosentan, simvastatin, and magnesium sulfate failed to improve patient outcomes.
  • Current best management includes maintaining adequate blood volume and pressure, nimodipine administration, and balloon angioplasty when indicated.
  • Despite advances, vasospasm remains a significant factor influencing outcomes after aneurysm rupture.

Conclusions:

  • While significant progress has been made in reducing morbidity and mortality from cerebral vasospasm, it continues to be a critical determinant of patient outcome.
  • Further research is needed to develop more effective preventative and therapeutic strategies.