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Performance guidelines for the partial thromboplastin time test
1Duke University Medical Center, Durham, NC.
The partial thromboplastin time (PTT) test is widely used as a screening test for the detection of hemophilia. It is also used to monitor patients on heparin anticoagulation. These proposed guidelines for the performance of this test, including comparable reference ranges, precision and sensitivity requirements are felt to be reasonable and attainable. Whether further progress will occur depends upon a perceived need by laboratorians, instrument and reagent manufacturers and government regulators that standardization of the PTT is desirable.
The partial thromboplastin time (PTT) test is widely used as a screening test for the detection of hemophilia. It is also used to monitor patients on heparin anticoagulation. These proposed guidelines for the performance of this test, including comparable reference ranges, precision and sensitivity requirements are felt to be reasonable and attainable. Whether further progress will occur depends upon a perceived need by laboratorians, instrument and reagent manufacturers and government regulators that standardization of the PTT is desirable.