[The effect of viral hepatitis A on thyroid function in adolescents with thyroid pathology]

In patients with virus hepatitis (VHA) without thyroid pathology, thyroid function decreases but during the recovery, it rapidly restores. In the presence of concomitant thyroid hyperplasia, its function in the acute period of VHA is inhibited to an ever greater degree and remains decreased during convalescence. This circumstance requires the use of replacement hormonal therapy. In cases of concomitant hypothyrosis, the initial level of thyroid hormones diminishes but it does not manifest itself by clinical disease exacerbation. In patients with concomitant toxic goiter, the hormonal status does not undergo any changes in mild forms of VHA, whereas in VHA of medium gravity and grave patterns of VHA, hyperthyroxinemia increases and the course of diffuse toxic goiter is exacerbated. Therefore, the treatment of patients with VHA associated with thyroid pathology should be conducted with regard to thyroid function.