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Japan Implantable Devices in Coronary Artery Disease (JID-CAD) study design
Akihiko Shimizu1, Takeshi Mitsuhashi2, Takashi Nitta3
1Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan.
Insights
The Japan Implantable Devices in Coronary Artery Disease (JID-CAD) study investigates appropriate therapies for patients with coronary artery disease (CAD) and implantable devices. It aims to clarify treatment strategies and outcomes in this population.
Area of Science:
- Cardiology
- Medical Devices
- Clinical Research
Background:
- Limited data exists on optimal therapies for Japanese coronary artery disease (CAD) patients with implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy defibrillators (CRT-Ds), or cardiac resynchronization therapy pacemakers (CRT-Ps).
- The Japan Implantable Devices in Coronary Artery Disease (JID-CAD) study was initiated to address this knowledge gap.
Purpose of the Study:
- To evaluate the current clinical landscape of appropriate device therapy in CAD patients with implantable devices in Japan.
- To explore the influence of catheter ablation and revascularization therapies on appropriate device therapy outcomes.
Main Methods:
- Prospective, multicenter, non-randomized, observational study design.
- Two-year follow-up with six-month intervals for all enrolled patients.
- Primary endpoint: administration of appropriate device therapy. Secondary endpoints: inappropriate therapy, mortality, hospitalization, and cardiovascular events.
Main Results:
- Data on appropriate device therapy administration in CAD patients with implantable devices is being collected.
- The study will analyze the impact of interventions like catheter ablation and revascularization on therapy outcomes.
Conclusions:
- The JID-CAD study will provide crucial insights into the management of CAD patients with implantable devices.
- Findings will inform clinical practice regarding appropriate device therapy and the role of adjunctive treatments.
Background:
There is little information regarding appropriate therapies for coronary artery disease (CAD) patients with implantable devices - such as implantable cardioverter-defibrillators (ICDs), cardiac resynchronization therapy devices (CRT-Ds) and cardiac resynchronization therapy pacemaker (CRT-P) devices - in Japan. To address this lack of information, we have launched the Japan Implantable Devices in Coronary Artery Disease (JID-CAD) study.
Methods:
This study has been designed as a prospective, multicenter, non-randomized and observational investigation. All patients will be followed up every six months over a two-year period. The primary endpoint will be the administration of appropriate device therapy. Secondary endpoints include administration of inappropriate therapy, death, hospitalization, or cardiovascular events.
Conclusion:
In this report, we discuss the current clinical situation of appropriate therapy, and how it is influenced by catheter ablation and revascularization therapy in patients with CAD.
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