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ESSCA results with the baseline series, 2009-2012: rubber allergens
Katharine L Warburton1, Andrea Bauer2, Mahbub M U Chowdhury3
1Department of Dermatology, The Leeds Teaching Hospitals NHS Trust, Leeds LS7 4SA, UK.
Contact Dermatitis
|September 5, 2015
Summary
Allergies to rubber additives like thiuram mix are declining, but carba mix allergy is increasing. This study highlights changing trends in rubber contact allergy, impacting preventive measures and occupational dermatitis.
Area of Science:
- Dermatology
- Allergology
- Occupational Health
Background:
- Allergic contact dermatitis from rubber allergens is a prevalent condition causing significant patient morbidity.
- Up-to-date data on contact allergy trends are crucial for effective prevention strategies and understanding evolving sensitization patterns.
Purpose of the Study:
- To analyze and report on the current patterns of patch test reactivity to various rubber allergens.
- To specifically assess reactivity to allergens included in the European baseline series.
Main Methods:
- Utilized data from the European Surveillance System on Contact Allergies (ESSCA) network.
- Analyzed patch test results from 12 European countries spanning the period 2009–2012.
- Employed statistical analysis, including the MOAHLFA index, to identify significant associations.
Main Results:
- A decline in contact allergy to thiuram mix was observed, with an overall prevalence of 1.87%.
- A significant increase in allergy to carba mix was detected, showing a prevalence of 2.29%.
- Sensitization rates to other rubber allergens remained largely stable.
- Confirmed a strong association between rubber allergy and occupational hand dermatitis.
Conclusions:
- Identified evolving patterns in sensitization to common rubber additives.
- Suggests that carba mix may warrant inclusion in the European baseline series for patch testing.
- Emphasizes the link between specific rubber allergies and occupational skin conditions.
