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Updated: Apr 4, 2026

Generation of a Novel Dendritic-cell Vaccine Using Melanoma and Squamous Cancer Stem Cells
Published on: January 6, 2014
Promise of cancer stem cell vaccine
Li Zhou1,2, Lin Lu1,3,4, Max S Wicha1
1a Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Abstract:
Dendritic cell (DC)-based vaccines designed to target cancer stem cells (CSC) can induce significant antitumor responses via conferring host anti-CSC immunity. Our recent studies have demonstrated that CSC-DC vaccine could inhibit metastasis of primary tumors and induce humoral immune responses against cancer stem cells. This approach highlights the promise of cancer stem cell vaccine in cancer immunotherapy.
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