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CT findings in melioidosis.

T Singcharoen

    Australasian Radiology
    |November 1, 1989
    PubMed
    Summary

    Computed tomography (CT) reveals diverse lung and pleural abnormalities in patients with melioidosis. Imaging findings include infiltrates, cavities, pleural effusion, and hepatosplenic microabscesses, aiding diagnosis.

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    Area of Science:

    • Radiology
    • Infectious Diseases
    • Medical Imaging

    Background:

    • Melioidosis is a serious infectious disease caused by Burkholderia pseudomallei.
    • Early diagnosis and treatment are crucial for improving patient outcomes.
    • Computed tomography (CT) plays a vital role in visualizing the extent and nature of melioidosis-related pathology.

    Observation:

    • This study presents CT findings in five patients diagnosed with melioidosis.
    • Diverse pulmonary manifestations were observed, including upper lobe infiltrates with or without cavities and lower lobe consolidation.
    • Extrapulmonary involvement was noted, such as hepatosplenic microabscesses in one case.

    Findings:

    • Characteristic CT findings in melioidosis include lobar consolidation, often in the upper lobes, and the presence of thin-walled cavities.
    • Pleural involvement is common, ranging from small nodules and effusions to more severe complications like hydropneumothorax and fibrothorax.
    • Hepatosplenic microabscesses represent a significant extrapulmonary manifestation detectable by CT.

    Implications:

    • CT imaging is essential for the comprehensive assessment of melioidosis, guiding clinical management.
    • Recognizing these diverse CT patterns can aid radiologists and clinicians in suspecting and diagnosing melioidosis, particularly in endemic areas.
    • Understanding the spectrum of CT findings facilitates the identification of complications and informs prognosis.

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