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Spiny Papules in an Immunosuppressed Child
Nicholas V Nguyen1, Arelis Burgos1,2, Lori Prok1,2
1Department of Dermatology, School of Medicine, University of Colorado, Aurora, Colorado.
Pediatric Dermatology
|September 5, 2015
Summary
Trichodysplasia spinulosa, a rare polyomavirus infection, presents as spiny facial papules in immunosuppressed individuals. This case highlights its recognition in a child with leukemia, emphasizing diagnostic and therapeutic options.
Area of Science:
- Dermatology
- Virology
- Oncology
Background:
- Trichodysplasia spinulosa is a rare folliculocentric polyomavirus infection.
- It is typically observed in immunocompromised patients.
Observation:
- A 7-year-old boy with pre-B-cell lymphoblastic leukemia developed facial folliculocentric spiny papules.
- Histological examination showed hypertrophic hair bulbs, expanded inner root sheath, and eosinophilic trichohyalin granules.
Findings:
- The case confirms trichodysplasia spinulosa in an immunosuppressed pediatric oncology patient.
- Characteristic histological features of the infection were identified.
Implications:
- This case raises awareness of trichodysplasia spinulosa as a rare but identifiable condition.
- It underscores the importance of recognizing this entity for appropriate diagnosis and treatment in immunocompromised individuals.
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