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Coexistent Nodal Diffuse Large B-Cell Lymphoma With Extrapulmonary Tuberculosis: A Rare Case.
Ritesh Sachdev1, Rajan Duggal2, Krati Agrawal2
1Medanta-The Medicity Hospital, Gurgaon, India sachdev05@gmail.com.
International Journal of Surgical Pathology
|September 5, 2015
Summary
This study reports a rare case of diffuse large B-cell lymphoma coexisting with extrapulmonary tuberculosis in a patient's lymph nodes. This finding is significant as it is the second such global case and the first in India.
Area of Science:
- Oncology
- Infectious Diseases
Background:
- Extrapulmonary tuberculosis (TB) coexisting with lymphoma in the same organ is uncommon.
- Hodgkin's lymphoma and low-grade non-Hodgkin's lymphoma are typically associated with extrapulmonary TB.
Observation:
- A 60-year-old male presented with fever, loss of appetite, and weakness.
- Generalized lymphadenopathy was observed during investigation.
- Cervical lymph node biopsy revealed concurrent diffuse large B-cell lymphoma and extrapulmonary tuberculosis.
Findings:
- This case represents the second documented instance worldwide of diffuse large B-cell lymphoma coexisting with extrapulmonary tuberculosis.
- This is the first reported case of this specific co-occurrence in India.
Implications:
- Highlights the importance of considering co-infections in lymphoma patients, particularly in endemic regions for tuberculosis.
- Contributes to the limited literature on rare lymphoma-tuberculosis co-occurrences, potentially influencing diagnostic and treatment strategies.
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