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Infant feeding and risk of severe diarrhoea in Basrah city, Iraq: a case-control study
Insights
Bottle-feeding significantly increases infant diarrhea hospitalization risk, especially exclusive bottle-feeding. Breastfeeding, alone or with food, is the safest feeding mode for infants aged 2-11 months.
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Infant feeding practices are critical determinants of child health.
- Diarrheal diseases remain a leading cause of infant morbidity and mortality globally.
- Understanding the impact of feeding modes on diarrheal disease risk is essential for public health interventions.
Purpose of the Study:
- To investigate the association between infant feeding modes and the risk of hospitalized diarrhea.
- To compare the risks associated with exclusive breastfeeding, partial breastfeeding, and bottle-feeding in infants aged 2-11 months.
Main Methods:
- A case-control study was conducted in Basrah city involving 597 infants hospitalized with diarrhea (cases) and 723 healthy controls.
- Data on feeding modes and other potential confounding variables were collected and analyzed.
- Statistical analysis controlled for confounding factors to assess the relative risks associated with different feeding practices.
Main Results:
- For infants aged 2-5 months, exclusive breastfeeding or breastfeeding with food showed the lowest risk of diarrhea hospitalization.
- Bottle-feeding was associated with significantly higher risks, with odds ratios of 55 (2-3 months) and 37 (4-5 months) compared to exclusive breastfeeding.
- For older infants (6-11 months), non-breastfeeding, particularly exclusive bottle-feeding, posed a significant risk, while partial breastfeeding modes showed similar risks.
Conclusions:
- Bottle-feeding is a major risk factor for hospitalized diarrhea in infants, especially in younger age groups.
- Breastfeeding, whether exclusive or partial, offers significant protection against severe diarrheal disease.
- Public health strategies should promote and support breastfeeding to reduce the burden of infant diarrhea.
Abstract:
A case-control study of the relationship between feeding mode and risk of hospitalized diarrhoea in infants (aged 2-11 months) in Basrah city was conducted between September 1983 and May 1984. A total of 597 cases were recruited from among infants admitted with diarrhoea to the major paediatric hospital in the city, while 723 controls were recruited from among healthy infants attending any of the seven maternal and child health clinics in Basrah. A variety of potentially confounding variables were controlled in the analysis. For infants aged 2-5 months, breast-feeding alone or breast-feeding plus food were the least risky feeding modes. Bottle-feeding was dangerous and bottle-feeding alone was associated with a risk of 55 among infants aged 2-3 months, and 37 among infants aged 4-5 months, relative to exclusive breast-feeding. For older infants (6-11 months), the risks of hospitalized diarrhoea were not significantly different among different partial breast-feeding modes, but non-breastfeeding was dangerous, especially exclusive bottle-feeding. Food intake was associated with a reduced risk of severe diarrhoea among bottle-fed infants but not with an increased risk among breast-fed infants. Among bottle-fed infants, no association was found between risk of severe diarrhoea and method of bottle-cleaning. Previous breast-feeding conferred no current protection.
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