Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Subacute thyroiditis associated with systemic multi-organ disorders.

M Kimura1, N Amino, K Takada

  • 1Department of Laboratory Medicine, Osaka University Medical School, Japan.

Endocrinologia Japonica
|December 1, 1989
PubMed
Summary

Subacute thyroiditis, typically self-limited, may involve multiple organs. This case study reveals inflammation extending beyond the thyroid to the liver, pancreas, and spleen.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Congenital hypothyroidism caused by a mutation in the Na+/I- symporter.

Nature genetics·1997
Same author

[Intra-individual and seasonal variations of thyroid function tests in healthy subjects].

Rinsho byori. The Japanese journal of clinical pathology·1996
Same author

Loss of biological activity of human chorionic gonadotropin (hCG) by the amino acid substitution on the "CMGCC" region of the alpha-subunit.

Molecular and cellular endocrinology·1994
Same author

[The background of the "Certification System for Certified Clinical Laboratory Physicians" and "Curriculum for Postgraduate Training in Clinical Pathology/Laboratory Medicine"].

Rinsho byori. The Japanese journal of clinical pathology·1994
Same author

[Molecular genetics of congenital isolated thyrotropin deficiency].

Nihon rinsho. Japanese journal of clinical medicine·1994
Same author

Ionizing radiation and autoimmunity. Induction of autoimmune disease in mice by high dose fractionated total lymphoid irradiation and its prevention by inoculating normal T cells.

Journal of immunology (Baltimore, Md. : 1950)·1994

Area of Science:

  • Endocrinology
  • Immunology
  • Gastroenterology

Background:

  • Subacute thyroiditis is commonly considered a self-limiting inflammatory condition affecting the thyroid gland.
  • This study presents serial observations of a patient with subacute thyroiditis.

Observation:

  • The patient exhibited destructive thyrotoxicosis with elevated acute phase reactants and erythrocyte sedimentation rate.
  • Additional findings included liver dysfunction (elevated ALT, ALP, gamma-GTP, LAP), mild anemia, glucose intolerance, increased pancreatic enzymes, splenomegaly, and elevated peripheral Leu 7 positive (NK/K) cells.

Findings:

  • All observed abnormalities resolved as the patient recovered from the illness.
  • The inflammatory process in this patient was not confined to the thyroid gland.

Related Experiment Videos

Implications:

  • These findings suggest that subacute thyroiditis can manifest as a systemic multi-organ disease.
  • The liver, pancreas, and spleen were identified as additional organs involved in the inflammatory process.