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Published on: July 19, 2024
Intraoperative pathology consultation for pulmonary lesions: errors and deferrals
1Department of Laboratory Medicine and Pathology, School of Medicine, Uludag University Gorukle, Nilufer, Bursa, Turkey.
Abstract:
The accuracy rate of frozen section constitutes an important step of quality assessment step in pathology practice. This study aimed to investigate pulmonary lesions that were incorrectly diagnosed or postponed for routine examination by pathologists at frozen section examination; it also aimed to discuss the reasons for difficult diagnoses and the various clues enabling the correct diagnosis to be made when such lesions are encountered. This study retrospectively reviewed the medical data of the thoracic surgery cases that underwent frozen section examination between 2009 and 2014. Frozen section errors and deferrals were identified in 25 cases. Fourteen (56%) lesions were of pulmonary parenchymal origin and 11 (44%) were of pleural origin. The number of cases in which the pathologists postponed the diagnosis without making any approach was 14. Of these, 9 (64%) were benign lesions such as bronchiectasis, fibrosis anthracosis, chronic inflammatory cell infiltration, chronic pleuritis, and mesothelial proliferation. The number of misdiagnosed cases was 11. Of these, 7 (64%) were of pulmonary and 4 (36%) were of pleural origin. Because the examination techniques of each pathology department may differ from one another, the comparative examination of frozen sections and routine sections would aid in becoming familiar with various pathologies and would be beneficial for pathologists in minimizing their diagnostic errors.
Insights
Frozen section accuracy in pathology is crucial. This study identified diagnostic errors and delays in pulmonary and pleural lesions, offering insights to improve frozen section diagnosis.
Area of Science:
- Pathology
- Thoracic Surgery
- Diagnostic Accuracy
Background:
- Frozen section examination is a critical component of intraoperative pathology.
- Accurate frozen section diagnosis is essential for guiding surgical decisions.
- Diagnostic errors or delays can impact patient management.
Purpose of the Study:
- To investigate errors and diagnostic postponements in frozen section examinations of thoracic lesions.
- To identify reasons for difficult diagnoses in frozen sections.
- To determine clues for improving the accuracy of frozen section diagnoses.
Main Methods:
- Retrospective review of medical data for thoracic surgery cases.
- Analysis of cases undergoing frozen section examination between 2009 and 2014.
- Identification and categorization of frozen section errors and deferrals.
Main Results:
- 25 cases (14 pulmonary, 11 pleural) had frozen section errors or deferrals.
- 14 diagnoses were postponed, with 9 being benign lesions.
- 11 cases were misdiagnosed (7 pulmonary, 4 pleural).
Conclusions:
- Frozen section accuracy for pulmonary and pleural lesions requires attention.
- Understanding reasons for diagnostic difficulty is key to improvement.
- Comparing frozen and routine sections can help pathologists minimize errors.
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