Platelet-rich plasma for resistant oral erosions of pemphigus vulgaris: A pilot study
Related Experiment Video
Updated: Apr 4, 2026

Platelet-Rich Plasma Lysate for Treatment of Eye Surface Diseases
Published on: August 2, 2022
Mohamed Hussein Medhat EL-Komy1, Akmal Saad Hassan1, Heba Mohammed Abdel Raheem1
1Department of Dermatology, Faculty of Medicine, Cairo University, Egypt.
Abstract:
Oral erosions and ulcers of pemphigus vulgaris (PV) are a debilitating condition that is usually difficult to treat. The wound healing properties of platelet-rich plasma (PRP) encouraged us to evaluate its usefulness in treatment of non-healing oral PV lesions. Seven patients with chronic oral PV, resistant to conventional therapy, were treated with weekly to monthly injections of PRP of affected mucosal membranes. All recruits reported improvement in pain and mastication and 6 of 7 patients had an improvement in pemphigus disease area index scores with PRP treatment. PRP injections seems to accelerate the healing process and decrease the pain and eating discomfort associated with the oral erosions and ulcers induced by PV.
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