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Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
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Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
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Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...
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Onco-nephrology: a decalogue.

Laura Cosmai1, Camillo Porta2, Maurizio Gallieni3

  • 1Division of Nephrology and Dialysis, Outpatient Clinic of Nephro-Oncology, Istituti Ospitalieri, Cremona, Italy Joint Italian Association of Medical Oncology (AIOM)/Italian Society of Nephrology (SIN) Working Group on Onco-Nephrology, Rome, Italy.

Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association
|September 6, 2015
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Summary

Onco-nephrology, the study of kidney and cancer, requires collaboration between nephrologists and oncologists. A proposed

Keywords:
AKICKDcancerdialysisnephrectomynephrotoxicity

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Area of Science:

  • Oncology
  • Nephrology
  • Onco-nephrology

Background:

  • Onco-nephrology addresses the intricate links between cancer and kidney disease.
  • Cancer patients frequently experience kidney-related complications, necessitating specialized care.

Purpose of the Study:

  • To propose a 'decalogue of onco-nephrology' outlining key collaborative areas for nephrologists and oncologists.
  • To guide the development of cutting-edge care for patients with co-existing cancer and kidney disease.

Main Methods:

  • This opinion piece presents a framework for onco-nephrology.
  • The framework, termed a 'decalogue', highlights ten critical areas for interdisciplinary focus.

Main Results:

  • The proposed decalogue covers acute kidney injury, chronic kidney disease, and nephrotoxicity from cancer therapies.
  • It also addresses paraneoplastic syndromes, post-nephrectomy care, renal replacement therapy, transplantation, and pain management.
  • Development of integrated guidelines and specific clinical trials for onco-nephrology are emphasized.

Conclusions:

  • A multidisciplinary onco-nephrology team is essential for optimal patient care.
  • This collaborative approach ensures high-quality, cutting-edge management in both acute and chronic settings for cancer patients with kidney disease.