Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis I: Introduction01:25

Endocarditis I: Introduction

777
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
777
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

804
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
804
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

334
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
334
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

582
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
582
Myocarditis II: Clinical Features and Diagnostic Tests01:27

Myocarditis II: Clinical Features and Diagnostic Tests

446
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
446
Myocarditis I: Introduction01:21

Myocarditis I: Introduction

598
Myocarditis is inflammation of the myocardium, which is the muscular layer of the heart.EtiologyMyocarditis has a diverse etiology, including a wide range of infectious and non-infectious causes:Infectious CausesViral: Common viruses include Coxsackie A and B, adenovirus, parvovirus B19, enteroviruses, and influenza A.Bacterial: Examples include infections caused by Streptococcus, Staphylococcus, and Mycoplasma species.Rickettsial: Infections like Rocky Mountain spotted fever can result in...
598

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Canada's "American-style" dental health system.

Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada·2026
Same author

A 67-year-Old Immunocompromised Male Presenting With Right Upper-Quadrant Abdominal Pain and Hepatic Lesions.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Commentary-presentation and reflections on renewing Canada's public health core competencies.

Canadian journal of public health = Revue canadienne de sante publique·2026
Same author

Increasing rates of Chlamydia trachomatis infection in Alberta, Saskatchewan, and Manitoba compared to Canada overall, between 1991 and 2022.

Infectious diseases now·2026
Same author

Enumeration, Phenotyping, and Clinical Associations of Tissue-Resident T Cells in the Ecto- and Endocervix of Women Attending a Colposcopy Clinic.

American journal of reproductive immunology (New York, N.Y. : 1989)·2026
Same author

Trauma, empowerment, and resilience: understanding the mental health concerns of people living with human immunodeficiency virus in Manitoba.

Frontiers in public health·2026

Related Experiment Video

Updated: Apr 4, 2026

Isolation of Valvular Endothelial Cells
11:04

Isolation of Valvular Endothelial Cells

Published on: December 29, 2010

21.1K

Quintessential Culture-Negative Endocarditis.

Yoav Keynan1, Lauren MacKenzie2, Philippe Lagacé-Wiens3

  • 1Department of Internal Medicine, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada; Department of Community Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.

The Canadian Journal of Cardiology
|September 7, 2015
PubMed
Summary
This summary is machine-generated.

Bartonella spp cause culture-negative endocarditis, often delaying diagnosis. This case highlights Bartonella quintana endocarditis, requiring valve replacement.

More Related Videos

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

19.8K
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

18.1K

Related Experiment Videos

Last Updated: Apr 4, 2026

Isolation of Valvular Endothelial Cells
11:04

Isolation of Valvular Endothelial Cells

Published on: December 29, 2010

21.1K
Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart
08:22

Isolation of Endocardial and Coronary Endothelial Cells from the Ventricular Free Wall of the Rat Heart

Published on: April 15, 2020

19.8K
Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

18.1K

Area of Science:

  • Infectious Diseases
  • Cardiology
  • Microbiology

Background:

  • Bartonella species are significant causes of culture-negative endocarditis.
  • This infection typically presents insidiously with fever and heart failure symptoms.
  • Diagnosis often relies on polymerase chain reaction (PCR) on resected valves.

Observation:

  • A case of Bartonella quintana endocarditis affecting mitral and aortic valves is presented.
  • The patient experienced severe valvular insufficiency and decompensated heart failure.
  • Bacterial superinfection with Streptococcus pneumoniae precipitated acute decompensation.

Findings:

  • Pathologic examination of the explanted valve was crucial for diagnosis.
  • Serologic and molecular testing confirmed Bartonella quintana as the causative agent.
  • The study underscores the diagnostic challenges of Bartonella endocarditis.

Implications:

  • Early recognition and diagnosis of Bartonella endocarditis are critical.
  • Prompt surgical intervention may be necessary in severe cases.
  • This case emphasizes the importance of considering Bartonella in culture-negative endocarditis.