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Large-Scale Multi-Omics Genome-Wide Association Studies Mo-GWAS: Guidelines for Sample Preparation and Normalization
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A guide to genome-wide association analysis and post-analytic interrogation

Eric Reed1, Sara Nunez1, David Kulp2

  • 1Department of Mathematics and Statistics, Mount Holyoke College, South Hadley, MA, U.S.A.

Statistics in Medicine
|September 8, 2015
PubMed

Keywords:
BioconductorHardy-Weinberg equilibrium (HWE)IBDManhattan plotQ-Q plotR codeSNP filteringUCSC Genome Browserancestrycall rategenome-wide association (GWA) studyheatmapheterozygosityimputationlambda statisticminor allele frequency (MAF)parallel processingprincipal component analysis (PCA)regional association plotrelatednesssample filteringstatistical genomicssubstructuretutorial

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