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Electrochemical sensing using boronic acids.

Meng Li1, Weihong Zhu, Frank Marken

  • 1Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. t.d.james@bath.ac.uk F.Marken@bath.ac.uk.

Chemical Communications (Cambridge, England)
|September 8, 2015
PubMed
Summary
This summary is machine-generated.

Boronic acid electrochemical sensors offer advanced methods for detecting biological analytes. This review highlights their progress in solution and surface processes for health diagnostics and biomolecule sensing.

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Area of Science:

  • Electrochemistry
  • Analytical Chemistry
  • Materials Science

Background:

  • Boronic acids form cyclic complexes with diols and interact with Lewis bases.
  • Boronic acid functionalized materials are used in functional materials, biomolecule sensing, and microbial electrochemistry.
  • They are widely developed as chemical sensors for health diagnostics.

Purpose of the Study:

  • To review recent advancements in boronic acid-based electrochemical sensors.
  • To cover both solution and surface processes for detecting biological analytes.
  • To provide insights for chemists, engineers, biochemists, and the sensor community.

Main Methods:

  • Review of recent progress in boronic acid-based electrochemical sensor technology.
  • Analysis of applications in solution and surface processes.
  • Focus on detection of biological analytes.

Main Results:

  • Boronic acid sensors demonstrate significant progress in detecting biological analytes.
  • Applications span functional materials, biomolecule/protein attachment and sensing, and microbial electrochemistry.
  • Development as chemical sensors and tools in health diagnostics is rapidly advancing.

Conclusions:

  • Boronic acid electrochemical sensors are a rapidly advancing field with broad applications.
  • Continued research promises enhanced capabilities for diagnostics and biomolecular analysis.
  • This review serves as a valuable resource for researchers in related disciplines.