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Published on: March 18, 2015
Unusual compounds from Galium mollugo and their inhibitory activities against ROS generation in human fibroblasts
Nassima Chaher1, Stéphanie Krisa2, Jean-Claude Delaunay2
1Laboratoire de Biochimie Appliquée, Faculté des Sciences de la Nature et de la vie, Université de Bejaia, Bejaia 06000, Algérie.
Abstract:
Three unusual dioxatricyclodecenone compounds, mollugoside A, E-mollugoside B and Z-mollugoside B and, together with known flavonoids, were isolated from the aerial parts of Galium mollugo collected in north-eastern Algeria. Their structures were elucidated by analysis of spectroscopic data, including 1D and 2D NMR. Flavonoids and mollugoside A significantly reduced reactive oxygen species (ROS) generation in human fibroblasts.
