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Published on: February 24, 2023
A case of Mediterranean spotted fever associated with severe respiratory distress syndrome
Boris Dželalija1, Volga Punda-Polić2, Alan Medić3
1Department of Infectious Diseases, Zadar General Hospital, Zadar, Croatia; Department of Microbiology, Split University School of Medicine, Split, Croatia.
Abstract:
Mediterranean spotted fever (MSF) is usually a mild endemic rickettsial disease occurring in southern Croatia. We have reported the clinical and epidemiological characteristics of an acute MSF case associated with severe respiratory distress syndrome and hemodynamical instability. The patient recovered completely after antimicrobial treatment. Indirect immunofluorescence assay (FOCUS Diagnostics Inc.) was performed to detect IgM and IgG antibodies to Rickettsia conorii. A significant increase of both IgM and IgG antibody titres found in paired acute- and convalescent-phase serum confirmed the diagnosis of acute MSF.
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