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Updated: Apr 4, 2026
Lung Rapid Recovery Procurement Combined with Abdominal Normothermic Regional Perfusion in Controlled Donation after Circulatory Death
Published on: August 15, 2022
A case of diffuse panbronchiolitis, associated with severe pulmonary hypertension, managed with bilateral lung
Yasutaka Onishi1, Tetsuji Kawamura1, Akie Morimoto1
1Department of Respiratory Medicine, National Hospital Organization, Himeji Medical Center, Honnmachi 68, Himeji City 670-8520, Hyogo, Japan.
Abstract:
Diffuse panbronchiolitis (DPB) is a chronic respiratory disease that mainly involves the respiratory bronchioles, and has historically been associated with a very poor prognosis. The development of long-term low dose macrolide therapy in the 1980s has dramatically improved the prognosis of DPB. Nevertheless, some cases are resistant to macrolide therapy, and ultimately develop severe respiratory failure and pulmonary hypertension; in such cases lung transplantation is a viable treatment option. Here we report the case of a 40-year-old patient with a 20-year history of DPB, who underwent bilateral lung transplantation due to severe respiratory failure with pulmonary hypertension.
