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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Related Experiment Video

Updated: Apr 4, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
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Primary umbilical endometriosis.

M J Claas-Quax1, M L Ooft2, F J H Hoogwater3

  • 1Department of Obstetrics and Gynaecology, Sint Antonius Hospital, Nieuwegein, The Netherlands.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|September 8, 2015
PubMed
Summary

This case study details a rare instance of cutaneous endometriosis in a 27-year-old woman experiencing cyclical umbilical bleeding. Diagnosis was confirmed through MRI, cytology, and pathology, highlighting this unusual presentation of endometriosis.

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Area of Science:

  • Gynecology
  • Dermatology
  • Pathology

Background:

  • Cutaneous endometriosis is a rare condition.
  • It is even rarer when it occurs without prior surgical history.

Observation:

  • A case of a 27-year-old woman presented with catamenial bleeding from her umbilicus.
  • This cyclical bleeding from the navel is an uncommon manifestation.

Findings:

  • Magnetic Resonance Imaging (MRI) was utilized for initial assessment.
  • Cytological and pathological examinations definitively confirmed the diagnosis of endometriosis.
  • The findings underscore the importance of considering endometriosis in cases of cyclical umbilical bleeding.

Implications:

  • This case expands the understanding of endometriosis presentations.
  • It highlights the diagnostic challenges and differential diagnoses for umbilical bleeding.
  • Further research into rare cutaneous endometriosis cases is warranted.