[Prognostic factors in epithelial ovarian cancers--clinical significance of morphologic indicators]

The main factors influencing prognosis (staging, histologic classification and grading, lymphocyte infiltration etc.) in 110 patients with epithelial ovarian cancers were analysed by life table technique to obtain 5 year cumulative survival rate. Multivariate statistical analysis (Cox Model) was used in 88 patients in order to find out the most important prognostic factor. The results showed that degree of lymphocyte infiltration in the tumor was the most important; the next was clinical factors; moreover, the amount of residual tumor was more significant than staging. Specimen from reoperation revealed less lymphocyte infiltration than that from the first operation. The degree of lymphocyte infiltration as an expression of the local host defence can be used as a good prognostic indicator.