[Primary malignant lymphoma of the right parietal bone in childhood--a case report]

Primary malignant lymphoma of the bone is quite rare in childhood. Its incidence was reported to be less than 1% in Japanese patients. A 14 year-old boy admitted to Mie University Hospital because of tumor of the skull in August 1988 is reported. Biopsy of the tumor revealed non-Hodgkin's lymphoma (diffuse large cell type). Bone marrow aspiration on admission showed infiltration of lymphoma cells. Surface marker analysis of lymphoma cells in bone marrow was performed by a panel of monoclonal antibodies. The surface phenotype of lymphoma cells conformed with that of non-T, non-B lymphoid cells. The patient was treated by high-risk lymphoma protocol formulated in the Department of Pediatrics, Mie University and achieved complete remission.