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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
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[Anaemia and chronic diseases]
Philippe Chassagne1, Laetitia Amalou1, Anne-Lyse Thillard1
1Service de médecine interne gériatrique, CHU Rouen, France.
Geriatrie Et Psychologie Neuropsychiatrie Du Vieillissement
|September 9, 2015
Summary
Anemia affects 20% of older adults, often due to multiple health issues like chronic kidney disease and iron deficiency. This condition worsens health outcomes, increasing mortality and hospitalizations in the elderly.
Area of Science:
- Gerontology
- Internal Medicine
- Hematology
Background:
- Anemia prevalence is 20% in patients aged 65 years and older.
- Anemia in the elderly is frequently multifactorial, linked to comorbidities.
- Associated conditions include chronic renal failure, inflammatory diseases, nutrient deficiencies, and iron deficiency.
Purpose of the Study:
- To highlight anemia as a significant health concern in the elderly.
- To underscore the prognostic value of anemia in older populations.
- To explore the relationship between anemia and adverse health outcomes.
Main Methods:
- Review of existing literature on anemia in older adults.
- Analysis of comorbidities associated with anemia in this demographic.
- Examination of anemia's impact on morbidity and mortality.
Main Results:
- Anemia is a marker of general health status in the elderly.
- Anemia is associated with increased morbidity, including unplanned hospitalizations.
- Anemia correlates with higher mortality rates in older individuals.
Conclusions:
- Anemia can be both a consequence and a severity marker of chronic diseases in the elderly.
- Anemia negatively impacts prognosis, particularly in conditions like chronic cardiac failure.
- Anemia is recognized as a component of frailty in older adults.
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