[Kidney function in women with pregnancy-induced hypertension]

The authors examined 74 women in III trimester (29-40 week), among them 44 women with hypertension induced by pregnancy (group examined) and 30 healthy women (control group). The blood serum of these women was studied for: creatinine, urea, uric acid, electrolytes K+ and Na+. Besides, the blood was studied for acid-base equilibrium (apparatus Corning type 128). The 24-hour urine of the two groups was studied for the concentrations of ions: 1) ammonium (NH4+), 2) hydrogen (H+) and 3) potassium and sodium (K+ and Na+). The authors also made the endogenic creatinine clearance (Ckr). The results were calculated statistically. The women with hypertension induced by pregnancy had in their blood serum an increase in the concentration of creatinine, urea and uric acid. As to the parameters of acid-base equilibrium, the authors found an increase in pCO2. Besides, the women with this kind of hypertension had: a decrease in the excretion of ions NH4+ and H+ in the urine, a decrease of Ckr with electrolytes K+ and Na+ being within the normal range.