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Palmoplantar lichen planus successfully treated with acitretin.
Berna Solak1, Rabia Oztas Kara1, Mustafa Kosem2
1Department of Dermatology, Sakarya University, School of Medicine, Sakarya, Turkey.
BMJ Case Reports
|September 9, 2015
Summary
Palmoplantar lichen planus (PPL), a rare condition affecting hands and feet, was effectively treated with acitretin. This case highlights acitretin as a promising therapy for PPL, showing significant improvement within two months.
Area of Science:
- Dermatology
- Clinical Case Study
Background:
- Palmoplantar lichen planus (PPL) is a rare variant of lichen planus (LP).
- PPL specifically affects the palms and soles, presenting distinct clinical features from classic LP.
Observation:
- A 50-year-old male presented with hyperkeratotic papules and plaques on his palms and soles.
- Skin biopsy confirmed the diagnosis of palmoplantar lichen planus.
- The patient exhibited a positive clinical response to oral acitretin therapy.
Findings:
- Acitretin treatment led to significant improvement in PPL symptoms within a two-month period.
- The patient's response suggests acitretin is a viable therapeutic option for PPL.
- Early diagnosis and prompt treatment are key for managing PPL.
Implications:
- This case suggests acitretin may be a favorable treatment for palmoplantar lichen planus.
- Further research into acitretin's efficacy in larger PPL cohorts is warranted.
- The findings contribute to the understanding of PPL management strategies.

