Related Experiment Video
Updated: Apr 4, 2026

Transcutaneous Microcirculatory Imaging in Preterm Neonates
Published on: December 31, 2015
Small Baby Unit Improves Quality and Outcomes in Extremely Low Birth Weight Infants
Mindy Morris1, John Patrick Cleary2, Antoine Soliman3
1Division of Neonatology, CHOC Children's Hospital, Orange, California; and mmorris@choc.org.
Insights
A dedicated Small Baby Unit (SBU) improved outcomes for extremely low birth weight (ELBW) infants. This multidisciplinary approach reduced infections, growth restriction, and resource use, enhancing care for vulnerable newborns.
Area of Science:
- Neonatal Medicine
- Pediatric Quality Improvement
Background:
- Survival rates for extremely low birth weight (ELBW) infants have increased, yet many face significant post-discharge challenges.
- A quality improvement initiative was needed to address the complex needs of ELBW infants.
Purpose of the Study:
- To implement and evaluate a multidisciplinary team-based quality improvement approach to enhance outcomes for ELBW infants.
Main Methods:
- Establishment of a specialized Small Baby Unit (SBU) for infants born at ≤28 weeks gestation and <1000 g.
- Care provided by a consistent, multidisciplinary team utilizing evidence-based guidelines and standardized checklists.
- Implementation of ongoing educational and process-improvement collaborations within the SBU team.
Main Results:
- Significant reduction in hospital-acquired infections (39.3% to 19.4%, P < .001).
- Decreased incidence of growth restriction at discharge (62.3% to 37.3%, P = .001).
- Substantial decrease in resource utilization, including laboratory tests and radiographs (P < .001 for both).
Conclusions:
- Care within a dedicated SBU by a consistent multidisciplinary team, employing quality improvement methods, demonstrably improved ELBW infant outcomes.
- Sustained improvements necessitate ongoing team engagement and professional development.
Objective:
The survival rates for extremely low birth weight (ELBW) infants have improved, but many are discharged from the hospital with significant challenges. Our goal was to improve outcomes for this population by using a multidisciplinary team-based quality improvement approach.
Methods:
A unique program called the Small Baby Unit (SBU) was established in a children's hospital to care for the ELBW infant born at 28 weeks or less and weighing less than 1000 g at birth. These patients were cared for in a separate location from the main neonatal unit. A core multidisciplinary team that participates in ongoing educational and process-improvement collaboration provides care. Evidence-based guidelines and checklists standardized the approach.
Results:
Data from the 2 years before and 4 years after opening the SBU are included. There was a reduction in chronic lung disease from 47.5% to 35.4% (P = .097). The rate of hospital-acquired infection decreased from 39.3% to 19.4% (P < .001). Infants being discharged with growth restriction (combined weight and head circumference <10th percentile) decreased from 62.3% to 37.3% (P = .001). Reduced resource utilization was demonstrated as the mean number per patient of laboratory tests decreased from 224 to 82 (P < .001) and radiographs decreased from 45 to 22 (P < .001).
Conclusions:
Care in a distinct unit by a consistent multidisciplinary SBU team using quality improvement methods improved outcomes in ELBW infants. Ongoing team engagement and development are required to sustain improved outcomes.

