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Updated: Apr 4, 2026

Visualization of Candida albicans in the Murine Gastrointestinal Tract Using Fluorescent In Situ Hybridization
Published on: November 5, 2019
Candida albicans commensalism in the gastrointestinal tract
B Anne Neville1, Christophe d'Enfert2, Marie-Elisabeth Bougnoux3
1Institut Pasteur, Unité Biologie et Pathogénicité Fongiques, Département Mycologie, F-75015 Paris, France INRA, USC2019, F-75015 Paris, France.
Abstract:
Candida albicans is a polymorphic yeast species that often forms part of the commensal gastrointestinal mycobiota of healthy humans. It is also an important opportunistic pathogen. A tripartite interaction involving C. albicans, the resident microbiota and host immunity maintains C. albicans in its commensal form. The influence of each of these factors on C. albicans carriage is considered herein, with particular focus on the mycobiota and the approaches used to study it, models of gastrointestinal colonization by C. albicans, the C. albicans genes and phenotypes that are necessary for commensalism and the host factors that influence C. albicans carriage.
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