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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
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Methicillin-Resistant Staphylococcus aureus Colonization and Empyema: Does it Matter?

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  • 1Department of Surgery, Scott and White Memorial Hospital , Temple, Texas.

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Patients colonized with methicillin-resistant Staphylococcus aureus (MRSA) are significantly more likely to develop MRSA empyema. However, MRSA empyema did not impact patient outcomes or clinical management strategies.

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Area of Science:

  • Infectious Diseases
  • Pulmonary Medicine
  • Critical Care Medicine

Background:

  • The relationship between MRSA colonization and empyema culture results remains unclear.
  • This study investigated the hypothesis that MRSA colonization increases the likelihood of MRSA empyema.
  • The impact of MRSA-positive empyema on clinical management and patient outcomes was also examined.

Purpose of the Study:

  • To determine the association between MRSA colonization and MRSA empyema.
  • To evaluate if MRSA-positive empyema influences clinical management.
  • To assess the effect of MRSA empyema on patient outcomes.

Main Methods:

  • Retrospective review of 147 empyema patients from 2007-2010.
  • Analysis of demographics, MRSA colonization status, comorbidities, and culture results.
  • Bivariate testing and logistic regression were used to analyze data.

Main Results:

  • 10.8% of empyema patients were colonized with MRSA.
  • MRSA-colonized patients had a 75% rate of MRSA-positive empyema cultures versus 4.6% in non-colonized patients (p<0.001).
  • MRSA-positive empyema patients were more likely to be managed with tube thoracostomy alone (66.7%) compared to other culture results (p=0.043).

Conclusions:

  • MRSA-colonized patients hospitalized with empyema have a high probability of MRSA-positive cultures.
  • Empyema culture results and MRSA colonization status were not significant risk factors for poor discharge outcomes.