Related Experiment Video
Updated: Apr 4, 2026

Echocardiographic Assessment of Cardiac Anatomy and Function in Adult Rats
Published on: December 13, 2019
Ideal Cardiovascular Health During Adult Life and Cardiovascular Structure and Function Among the Elderly
Amil M Shah1, Brian Claggett2, Aaron R Folsom2
1From Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA (A.M.S., B.C., S.D.S.); Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (A.R.F., P.L.L.); Section of Cardiology, Baylor College of Medicine and Methodist DeBakey Heart and Vascular Center, Houston, TX (C.M.B.); and University of North Carolina Gillings School of Global Public Health, Chapel Hill (G.H.). ashah11@partners.org.
Maintaining ideal cardiovascular health from midlife into old age lowers heart disease risk and improves heart function in older adults. Consistent prevention efforts are key for long-term cardiovascular health.
Area of Science:
- Cardiology
- Public Health
- Gerontology
Background:
- Higher American Heart Association cardiovascular health scores (CVHS) are linked to reduced cardiovascular disease (CVD) incidence.
- The long-term impact of midlife CVHS on late-life CVD prevalence and cardiac function is not well understood.
Purpose of the Study:
- To investigate the association between CVHS attainment and changes over time with CVD prevalence and cardiac structure/function in older adults.
- To evaluate the long-term cardiovascular benefits of maintaining ideal cardiovascular health.
Main Methods:
- Utilized data from the Atherosclerosis in Communities (ARIC) study (1987-2013).
- Assessed 6 ideal CVHS metrics: nonsmoking, BMI, cholesterol, blood pressure, glucose, and physical activity.
- Analyzed CVHS attainment, change (slope per decade), and trajectory, correlating with CVD prevalence and echocardiographic measures.
Main Results:
- CVHS was generally low at baseline and decreased with age.
- Greater CVHS attainment and improvement over time were associated with lower CVD prevalence.
- Higher CVHS was linked to better left ventricular structure, systolic, and diastolic function in late life.
Conclusions:
- Achieving and improving ideal cardiovascular health from midlife to late life is associated with reduced CVD prevalence and enhanced cardiac function in elderly individuals.
- Consistent primordial and primary prevention efforts throughout life are crucial for mitigating the burden of CVD in older populations.
Related Concept Videos
The Effect of Aging on Tissues
Cognitive Development During Adulthood
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution
Pharmacodynamics in Geriatric Patients: Effects of Age
Drug Dosing: Geriatric Patients
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

