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Related Concept Videos

Introduction to Hemostasis01:05

Introduction to Hemostasis

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Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
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Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

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Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
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Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

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Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
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Extrinsic and Intrinsic Pathways of Hemostasis01:20

Extrinsic and Intrinsic Pathways of Hemostasis

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Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
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Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
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Disorders of Hemostasis01:24

Disorders of Hemostasis

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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
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Related Experiment Video

Updated: Apr 4, 2026

Application of Hemostatic Devices in Laparoscopic Hepatectomy
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New haemostat in thoracic surgery.

P Habal, N Omran, K Kovacicova

    Bratislavske Lekarske Listy
    |September 10, 2015
    PubMed
    Summary

    Resorbable oxidized cellulose hemostats effectively reduce blood loss and hospital stays in thoracic surgery, particularly for complex cases. This method also aids in managing post-operative drainage and inflammatory responses.

    Area of Science:

    • Thoracic Surgery
    • Surgical Hemostasis
    • Biomaterials

    Background:

    • Oxidized cellulose hemostats offer a promising method to minimize peroperative bleeding in major thoracic surgeries.
    • Their malleability and ease of application are advantageous, especially in patients with post-inflammatory thoracic complications.
    • Biodegradation of oxidized cellulose lowers pH, providing a sustained antibacterial effect.

    Purpose of the Study:

    • To retrospectively evaluate the impact of resorbable hemostats on post-operative blood loss.
    • To assess the effects on thoracic drainage duration, hospital stay, and inflammatory markers.
    • To compare outcomes between patients who received hemostats and a control group.

    Main Methods:

    • A retrospective study involving 48 patients (Group A) who underwent thoracic surgery with hemostat application.
    Keywords:
    Traumacel FAM OcW.fibrothoraxperoperative bleedingpostoperative bleeding

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  • A matched control group (Group B) of 48 patients without hemostat use, selected based on similar demographics, diagnosis, and surgical procedures.
  • Evaluation of post-operative blood loss, hematological profiles, drainage time, inflammatory response (CRP), and hospitalization duration.

    • Main Results:

    • Significant differences observed in hemoglobin and hematocrit levels post-operatively between the groups.
    • Reduced thoracic drainage time and shorter hospital stays were noted in the hemostat group.
    • A transient increase in C-reactive protein (CRP) was observed 12 hours post-application in the hemostat group, likely indicating aseptic pleurisy.

    Conclusions:

    • Resorbable oxidized cellulose hemostats are effective in reducing blood loss and improving patient outcomes in thoracic surgery.
    • The use of these hemostats can lead to shorter drainage times and hospitalizations.
    • While effective, the potential for aseptic pleurisy should be considered when interpreting post-operative inflammatory markers.