Related Experiment Video For CT colonography
Updated: Apr 4, 2026

Structured Approach to Colonoscopy Technique Optimization: A Single-Center Experience with Novice Endoscopists
Published on: July 11, 2025
Medicare cost of colorectal cancer screening: CT colonography vs. optical colonoscopy
Bruce Pyenson1, Perry J Pickhardt2, Tia Goss Sawhney3
1Milliman, One Pennsylvania Plaza, 38th Floor, New York, NY, 10019, USA. bruce.pyenson@milliman.com.
Purpose:
To compare the Medicare population cost of colorectal cancer (CRC) screening of average risk individuals by CT colonography (CTC) vs. optical colonoscopy (OC).
Methods:
The authors used Medicare claims data, fee schedules, established protocols, and other sources to estimate CTC and OC per-screen costs, including the costs of OC referrals for a subset of CTC patients. They then modeled and compared the Medicare costs of patients who complied with CTC and OC screening recommendations and tested alternative scenarios.
Results:
CTC is 29% less expensive than OC for the Medicare population in the base scenario. Although the CTC cost advantage is increased or reduced under alternative scenarios, it is always positive.
Conclusion:
CTC is a cost-effective CRC screening option for the Medicare population and will likely reduce Medicare expenditures for CRC screening.
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