Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension II: Pathophysiology01:29

Hypertension II: Pathophysiology

1.5K
Hypertension is a chronic condition in which the blood's force against artery walls is excessively high, posing risks such as heart disease. The condition's underlying mechanisms involve complex interactions among the cardiovascular, kidney, and autonomic nervous systems.Renin-Angiotensin-Aldosterone System (RAAS): This system significantly influences blood pressure regulation. When blood pressure decreases, the kidneys secrete renin. This enzyme transforms angiotensinogen, a plasma protein,...
1.5K
Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

723
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
723
Overview of Systemic Arteries01:11

Overview of Systemic Arteries

2.6K
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the...
2.6K
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

681
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
681
Blood Pressure01:24

Blood Pressure

11.5K
The movement of blood in a human body, commonly referred to as blood flow, is determined by the volume of blood that traverses a certain section of the bodily system per unit time. It is the rhythmic contraction of the heart's ventricles that primarily instigates this movement. As the ventricles contract, blood is forced into the prominent arteries, which then flow from areas of greater pressure to lower pressure areas. This movement continues into smaller arteries and arterioles and...
11.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical Management of Maculopathy in Papillorenal Syndrome: Insights From 2 Cases With PAX2 Mutations.

Journal of vitreoretinal diseases·2026
Same author

New marker for the detection of pre-retinopathy in patients with type 1 diabetes mellitus: systemic immuno-inflammation index.

BMC ophthalmology·2025
Same author

Comment on: Pentosan Polysulfate Maculopathy: Final Outcomes From a 4-Year Prospective Study of Disease Progression After Drug Cessation.

American journal of ophthalmology·2025
Same author

COVID-19's effects on microvascular structure in a healthy retina: an OCTA study.

International journal of ophthalmology·2025
Same author

Comment on: Retinal and Choroidal Circulation Impairments in Fanconi Anemia.

American journal of ophthalmology·2025
Same author

Comment on: Early Versus Delayed Vitrectomy for Vitreous Hemorrhage Secondary to Proliferative Diabetic Retinopathy.

American journal of ophthalmology·2025

Related Experiment Video

Updated: Apr 4, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

442

Choroidal thickness in systemic arterial hypertension.

Fahrettin Akay1, Fatih Cakir Gundogan2, Umit Yolcu3

  • 1Department of Ophthalmology, Izmir Military Hospital, Izmir - Turkey.

European Journal of Ophthalmology
|September 10, 2015
PubMed
Summary

Systemic arterial hypertension is linked to reduced choroidal thickness in young adults. This finding suggests potential vascular changes in the choroid due to elevated blood pressure.

More Related Videos

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

805
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

2.2K

Related Experiment Videos

Last Updated: Apr 4, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

442
Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography
03:35

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

805
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
07:18

Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

Published on: February 18, 2022

2.2K

Area of Science:

  • Ophthalmology
  • Cardiology
  • Vascular Biology

Background:

  • Systemic arterial hypertension (SAH) is a major risk factor for cardiovascular and cerebrovascular diseases.
  • Ocular microvasculature, including the choroid, may be affected by hypertension.
  • Assessing choroidal thickness offers a potential window into the ocular effects of SAH.

Purpose of the Study:

  • To evaluate choroidal thickness variations in young adults diagnosed with systemic arterial hypertension.
  • To compare choroidal measurements between hypertensive individuals and healthy controls.

Main Methods:

  • A prospective study involving 80 hypertensive patients and 80 healthy controls.
  • Choroidal thickness measured using spectral-domain optical coherence tomography (SD-OCT) at multiple points (subfoveal, nasal, and temporal to the fovea).
  • Blood pressure (SBP, DBP, MAP) recorded; only right eye data used for analysis.

Main Results:

  • Hypertensive subjects exhibited significantly lower mean choroidal thickness across all measured locations compared to controls (p<0.001).
  • No significant correlations were found between choroidal thickness and blood pressure levels (SBP, DBP, MAP) or disease duration.
  • Age was comparable between the hypertensive and control groups (p=0.945).

Conclusions:

  • Young adults with systemic arterial hypertension demonstrate reduced choroidal thickness.
  • This reduction may be attributed to arteriolar sclerosis and vascular constriction resulting from sustained high intravascular pressure within the choroid.