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[Physiology of pain]
K Messlinger1, H O Handwerker2
1Institut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstr. 17, 91054, Erlangen, Deutschland. messlinger@physiologie1.uni-erlangen.de.
Schmerz (Berlin, Germany)
|September 10, 2015
Summary
Pain research has evolved through various methods, from psychophysiology to modern imaging. Solving complex pain mechanisms requires interdisciplinary and international collaboration.
Area of Science:
- Physiology
- Neuroscience
- Pain Research
Background:
- Pain research has historically progressed alongside technological advancements.
- It has evolved from classical psychophysiology to electrophysiology and modern imaging techniques.
- German physiological pain research has a tradition of interdisciplinary and cross-border collaboration.
Purpose of the Study:
- To highlight the historical development of pain research methodologies.
- To emphasize the necessity of interdisciplinary and international collaboration in addressing current pain research questions.
- To underscore the integration of molecular techniques in contemporary biomedical research.
Main Methods:
- Review of historical and current methodologies in pain research.
- Analysis of the interdisciplinary nature of pain research networks.
- Focus on molecular techniques and imaging in nociceptive processing.
Main Results:
- Pain research development mirrors the methodological progress of different eras.
- Molecular techniques now dominate biomedical research, influencing pain studies.
- Interdisciplinary and international collaboration is crucial for current pain research.
Conclusions:
- Modern pain research relies on a broad physiological basis and advanced methodologies.
- Complex questions regarding intracellular signaling, immune interactions, and genetic underpinnings of pain require collaborative efforts.
- The future of pain research is intrinsically linked to interdisciplinary and international cooperation.
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