Related Experiment Video
Updated: Apr 4, 2026

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy
Published on: June 28, 2024
Surgical approaches for brainstem tumors in pediatric patients
Sergio Cavalheiro1,2, Kaan Yagmurlu3, Marcos Devanir Silva da Costa4
1Department of Neurosurgery, Pediatric Oncology Institute, Federal University of Sao Paulo, Sao Paulo, Brazil. sergiocavalheironeuro@gmail.com.
Purpose:
To analyze the pathways to brainstem tumors in childhood, as well as safe entry zones.
Method:
We conducted a retrospective study of 207 patients less than 18 years old who underwent brainstem tumor resection by the first author (Cavalheiro, S.) at the Neurosurgical Service and Pediatric Oncology Institute of the São Paulo Federal University from 1991 to 2011.
Results:
Brainstem tumors corresponded to 9.1 % of all pediatric tumors operated in that same period. Eleven previously described "safe entry zones" were used. We describe a new safe zone located in the superior ventral pons, which we named supratrigeminal approach. The operative mortality seen in the first 2 months after surgery was 1.9 % (four patients), and the morbidity rate was 21.2 %.
Conclusions:
Anatomic knowledge of intrinsic and extrinsic brainstem structures, in association with a refined neurosurgical technique assisted by intraoperative monitoring, and surgical planning based on magnetic resonance imaging (MRI) and tractography have allowed for wide resection of brainstem lesions with low mortality and acceptable morbidity rates.

