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An In Vitro Approach to Study Mitochondrial Dysfunction: A Cybrid Model
Published on: March 9, 2022
Social and ethical issues in mitochondrial donation
1Cardiff School of Social Sciences, Cardiff University, Cardiff, UK dimondr1@cardiff.ac.uk.
Introduction Or Background:
The UK is at the forefront of mitochondrial science and is currently the only country in the world to legalize germ-line technologies involving mitochondrial donation. However, concerns have been raised about genetic modification and the 'slippery slope' to designer babies.
Sources Of Data:
This review uses academic articles, newspaper reports and public documents.
Areas Of Agreement:
Mitochondrial donation offers women with mitochondrial disease an opportunity to have healthy, genetically related children.
Areas Of Controversy:
Key areas of disagreement include safety, the creation of three-parent babies, impact on identity, implications for society, definitions of genetic modification and reproductive choice.
Growing Points:
The UK government legalized the techniques in March 2015. Scientific and medical communities across the world followed the developments with interest.
Areas Timely For Developing Research:
It is expected that the first cohort of 'three parent' babies will be born in the UK in 2016. Their health and progress will be closely monitored.
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