Related Experiment Video
Updated: Apr 4, 2026
Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
Diffuse Calcifications of the Spleen in a Woman with Systemic Lupus Erythematosus
Aristeides G Vaiopoulos1, Meletios A Kanakis1, Kyriaki Katsouri2
1Department of Experimental Physiology, School of Medicine, University of Athens, 75 Mikras Asias Street, 11527 Athens, Greece.
Abstract:
Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disease, which affects a wide variety of organs including the spleen. Splenic involvement in SLE includes conditions such as splenomegaly, hyposplenism, infarction, and spontaneous rupture. However, only a few cases of splenic calcifications in patients with SLE have been reported. Herein, we present a case of a 24-year-old female diagnosed with SLE, in which we found diffuse splenic calcifications. The unique pattern of splenic calcifications in SLE contributes to the differential diagnosis from other conditions such as infections and other connective tissue diseases, which also cause calcifications in the spleen.
Related Concept Videos
01:15Secondary Lymphoid Organs
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
01:25Endocarditis II: Clinical Features of Infective Endocarditis
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT